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Who should consider a cash-pay GLP-1 program Cash-pay GLP-1 programs typically suit individuals who: Have a BMI of 27 or higher with a weight-related comorbidity (high blood pressure, sleep apnea, prediabetes), or BMI of 30 or higher Have insurance that excludes weight loss medications, or have no prescription drug coverage Have tried lifestyle interventions without achieving sustained results Want the convenience and privacy of a fully telehealth-based experience Are comfortable with weekly self-injection (or are interested in oral/sublingual alternatives) GLP-1 medications are not appropriate for everyone

The DNL pathway converts selectable carbon sources to FFAs, and the core enzymes involved in the process include acetyl-CoA carboxylase and fatty acid synthase [42]

doi: 10.1016/j.chest.2018.06.035 195 NiksereshtS.HiltonJ