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However, like other Khavinson peptides , Pinealon faces skepticism - most research conducted in Russia with limited Western replication, no FDA approval or large-scale international trials, mechanisms not fully elucidated despite decades of study, optimal dosing based on Russian protocols without rigorous dose-finding studies, and long-term safety data from clinical use rather than controlled trials

Competing interests The author, Jin-Kui Yang, is an associate editor of Current Medicine

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