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Heres what the research tells us about what happens when people stop these medications: The Weight Creeps Back Scientists followed patients who quit semaglutide after successful weight loss

, Meier, J

Wang, Comparison of pharmacokinetics of L-carnitine, acetyl-L-carnitine and propionyl-L-carnitine after single oral administration of L-carnitine in healthy volunteers., in Clin Invest Med, vol

They are downstream consequences of a chain of events that started with rapid weight loss and gallstones

Tirzepatide, another glucose-lowering medication known by the brand name Mounjaro, was approved for diabetes treatment in 2022 and is under fast-track review for weight loss