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Caroline Apovian, an endocrinologist who co-directs the Center for Weight Management and Wellness at Brigham and Women's Hospital in Boston, says that she doesn't use metformin "too much" for non-diabetic patients seeking weight loss these days

In addition, in vitro electrophysiological recordings further demonstrated that exendin-4 elicits an early fast excitatory response dose-dependently (Gullo et al., 2017)

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In contrast, patients prescribed this medication without a type 2 diabetes diagnosis are younger (average age of 47.5), more likely to be commercially insured (90.6%) and female (74.7%)

Eligibility, prescriptions, and dosing are based on provider evaluation