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To combat this systemic oxidative stress, the body relies on the Nrf2 signaling pathway, a genetic master switch that controls the expression of hundreds of antioxidant and detoxification genes

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Lastly, this review article provides new insights for treating ferroptosis in the testis

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A 2022 study in Frontiers in Pharmacology reported absorption, distribution, metabolism, and excretion data for the compound in rats and dogs, providing one of the first structured pharmacokinetic profiles in the peer-reviewed record [7]

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