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Because of its accumulation in the muscle and the heart, its ergogenic nature, and its role in energy metabolism, l-carnitine supplementation is proposed to play crucial roles in diseased populations where it has been shown to impact the management of ischaemic heart disease, myopathy, and peripheral arterial disease [22,23,24], as well as among healthy athletes where it has been shown to modulate the exercise capacity and recovery [25,26,27,28]