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Semaglutide appears to confer a greater effect on weight-related outcomes and LDL cholesterol reduction, even after adjustment for baseline differences

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If you burn through the dosing schedule rapidly then you have nothing powerful to fall back on at a later date

The FLOW trial achieved its primary endpoint with Ozempic 1mg, demonstrating a statistically significant and superior 24% relative risk reduction of kidney disease worsening, kidney failure (end-stage kidney disease), and death due to cardiovascular disease (4.9% absolute risk reduction at three years) compared to placebo, when added to standard of care