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HMGB1: A common biomarker and potential target for TBI, neuroinflammation, epilepsy, and cognitive dysfunction

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Cellular Therapy and Stem Cells for Insomnia offer hope by targeting the foundational dysfunctions: Hypothalamic Neurons: Key regulators of the circadian rhythm (especially in the suprachiasmatic nucleus), these neurons may become desynchronized, impairing sleep initiation and maintenance