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10.1016/j.mad.2014.01.002 301

J Am Chem Soc 145(35):1938719395 Bryant DA, Hunter CN, Warren MJ (2020) Biosynthesis of the modified tetrapyrrolesthe pigments of life

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Abbreviations ACC, Adrenocortical Carcinoma

(2) DADA2 denoising: Data was processed using dada2 ( Identification (amplicon sequence variants (ASVs)), diversity analysis, differential analysis, correlation analysis and functional prediction The qualified sequences with more than 97% similarity thresholds were allocated using dada2 to generate ASVs, and the samples with ASV counts less than 2 were filtered (Quast et al., 2013) with a confidence threshold of 70%