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In the STEP 3 randomised trial, once weekly semaglutide 2.4 mg used in obese adults without diabetes was associated with 4.9% incidence of gallbladder related disorders (mainly cholelithiasis) compared with 1.5% in the placebo group (1)

Mosconi L, Berti V, Dyke J, et al

Wegovy is administered once weekly via a simple subcutaneous injection, providing a convenient and effective way to manage weight without daily dosing