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Oral supplements are effective for mild deficiency and maintenance
In head-to-head clinical trials and real-world studies, tirzepatide consistently delivers greater weight loss (up to 22.5% vs 15%), superior A1C reduction (-2.3% vs -1.8%), and a higher proportion of patients achieving clinically meaningful weight loss thresholds
People with active cancers, untreated pituitary disorders, or certain metabolic conditions should avoid it unless specifically cleared by a medical provider (Mayo Clinic, 2024)
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