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Wyczanska M, Lange-Sperandio B

In fact, glutathione depletion is linked with a number of disease states and groups: Aging Athletic overtraining Major injuries and trauma Patients with wasting diseases such as HIV and AIDS Lung cancer Gut-based diseases such as Crohns and ulcerative colitis Chronic fatigue syndrome Alcoholism and fatty liver disease Diabetes and low glucose tolerance Cancer One of the most important things you can do to improve glutathione status is to remove or mitigate stressors that deplete glutathione

It is unclear whether this observation was due to the effects of time-restricted feeding (ie, intermittent fasting), a lower overall caloric intake with once-daily feeding (ie, caloric restriction), or whether pre-existing health conditions in the dogs may have affected how frequently they were fed

That is a meaningfully weaker claim than the titles phrasing implies, and it is the claim the evidence actually supports

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