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Tumours were induced, and upon presentation of clinical symptoms of tumour burden, animals were randomized and treated with 150 mg kg 1 5FU three times per week, with 250 mg kg 1 metformin or vehicle control delivered concurrently (Fig

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Frontiers in Endocrinology (Lausanne)

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## Side Effect Profiles All three medications share the common GLP-1 side effect profile because they all activate the same receptor

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The abdomen offers the largest injection area, with the entire zone at least two inches away from the belly button being suitable

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