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For tirzepatide, 503A (traditional) pharmacies had until February 18, 2025, and 503B (outsourcing) facilities had until March 19, 2025 to stop their GLP-1 production

Skipping dose escalation : Advancing too quickly through the titration schedule or starting at maintenance doses dramatically increases gastrointestinal adverse effects and treatment discontinuation

Similar to TMS techniques, tDCS targets left DLPFC primarily aiming to counterbalance the hyperactivity of the DMN secondary to hypoactivity of the frontoparietal network of the left DLPFC (123)

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