Ovarian cancer is the sixth most common malignancy among women in developed countries and the fifth leading cause of cancer-related death, representing a complex disease associated with poor survival rates.24 The combination chemotherapy of Paclitaxel (PTX) and Carboplatin (CARB) is considered the first-line treatment regimen for ovarian cancer.25 Both agents play distinct roles in inhibiting the growth of ovarian cancer through different mechanisms,26 and they are known to exert a synergistic anti-tumor effect by activating separate apoptotic signaling pathways, thereby potentially reducing drug resistance.25 The gonadotoxic effects of platinum-based chemotherapeutic agents have been demonstrated in numerous studies, both histopathologically and in terms of follicular development.27-29 In the present study, CARB administration led to significant histopathological damage in ovarian tissue, including follicular degeneration, prominent stromal edema, congestion, hemorrhage, inflammation, and fibrosis, particularly in the medullary region
In the context of aesthetics and skin brightening IV therapy, glutathiones most significant mechanism of action is its influence on melanogenesisthe process by which the body produces melanin (pigment)
The result is a compound that crosses the blood-brain barrier and exerts measurable effects on anxiety and stress response
Although the absolute risk is low, UK prescribing guidance for similar agents recommends that patients are counselled about this risk and advised to seek immediate medical attention if they develop sudden, severe abdominal pain
butyricum can prevent AP, possibly by inhibiting neutrophil and dendritic cell infiltration in the pancreas
