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7 PIONEER 7 The PIONEER 7 trial, like PIONEER 3, compared oral semaglutide against 100-mg sitagliptin, although this trial differs in that it allowed for flexible dose adjustments of oral semaglutide

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While co-administration with lixisenatide or dulaglutide reduced warfarins peak concentration by 19% and 22% respectively, the International Normalized Ratio (INR) stayed consistent, and no bleeding events were reported

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