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Finally, not all genetic roads lead to the immune system, and the heterogeneity of MS outcome also points toward intrinsic CNS molecular targets (International Multiple Sclerosis Genetics Consortium, 2021

Individuals commonly report: Vivid or disturbing dreams Headaches Insomnia Excessive sweating Gastrointestinal issues (vomiting, diarrhea) Tremors Irritability or agitation Confusion Dizziness Pins and needles sensations Irregular heartbeat Blurred vision Ringing in the ears (tinnitus) Depression or heightened anxiety Light flashes and electric shock-like feelings in the limbs and brain Discontinuation syndrome may further manifest as nausea, sensory disturbances, flu-like symptoms, balance problems, and heightened emotional responses (hyperarousal)

The role of aberrant mitochondrial bioenergetics in diabetic neuropathy

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