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-KG can also be exported to the cytosol to be carboxylated into citrate through isocitrate dehydrogenase 1 (IDH1) and further into acetyl-CoA for de novo fatty acid synthesis (Fendt et al., 2013)

Use the formula: Volume (mL) = Peptide Mass (mg) / Desired Concentration (mg/mL)

So, rather than focus on just the subjective nature of pain, let's talk about the absolute qualities of pain, and the absolute qualities of pleasure, so that we can learn how to navigate those two experiences in ways that serve us each better

Pulsatile dosing: Some experiment with dose cycling (e.g., one month on, one month off) to minimize tolerance development