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This initial dose serves primarily as a tolerability step rather than a therapeutic dose, allowing the body to adjust to the medication

Thats why its a good idea to check your thyroid labs before starting and again about six to eight weeks after

[] Third, Yabe et al [] reported nasopharyngitis as a common adverse with semaglutide use which may facilitate mouth breathing and dry mouth

The strategy employed has been to link GLP-1 or glucagon receptor agonists to nuclear hormones such as oestrogens, thyroid hormones and dexamethasone (reviewed in [64, 96, 99])

Since Zepbound can already cause gastrointestinal side effects like nausea or indigestion, avoiding NSAIDs like ibuprofen can help minimize further irritation