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D2, encoded by DIO2 gene, is primarily expressed in the thyroid, brain, anterior pituitary and brown adipose tissue, where contributes local conversion of T4 in T3

Long-term risks of surgery include nutritional deficiencies, osteoporosis, bone fractures, hyperinsulinemic hypoglycemia need to be carefully balanced with metabolic benefits for individual patients

Although MASLD cardiometabolic criteria were not a requirement for trial enrolment, almost all participants ( 99%) had at least one MASLD cardiometabolic criterion, emphasising the metabolic burden of MASH

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The role of AMP-activated protein kinase in the action of ethanol in the liver