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Conclusions from 67 Cu uptake and release measurements performed in hypothalamic slices by the presence of action potential blocker tetrodotoxin [231, 232] or determination of depolarization-induced copper release from nerve endings by AAS [225] raised the concept of copper signalling in the brain

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Intraperitoneal (i.p.) injection of NAC to rodents increased GSH in brain and synaptosomes and offered protection against peroxynitrite, hydroxyl radicals, acrolein, and oxidative stress induced by 3-nitro-propionic acid [40