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On the other hand, Th1/Th17 differentiation, induced by increased D3R expression on intestinal CD4+ T cells, the induction of ROR-t expression by D5R signaling in dendritic cells, and the increased IL-23 and IL-12 resulting from D5R signaling, contributes to the persistence of chronic inflammation (138)

doi: 10.1182/blood-2013-05-500207 116 LuHLinJXuCSunMZuoKZhangXet al

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