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216 Senescent cells secrete SASP factors, which include many inflammatory factors (such as IL-6, IL-1, and TNF-) and growth factors

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Ongoing Adjustment and Planning Dosage and duration are adjusted based on response

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A few patients developed pancreatitis, a serious inflammation of the pancreas

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The different mutations in SLC22A5 probably give rise to differences in severity/onset of the disease

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