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We used FineGray sub-distribution hazard model analyses adjusted for sex and age to assess the association of sociodemographic variables, comorbidities and co-medications (defined in ESM Table 2) with the risk of treatment discontinuation

However, the inflammatory response surrounding the herniation, the condition of the annulus fibrosus, and the health of supporting musculature all represent potential targets

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Even so, the thyroid-specific signal is less robust than the intestinal benefit, and the literature remains heterogeneous in sample size, design, and outcome definition (6471)