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Again, similar to the results observed in mouse caSMCs, GLP-1(2836) activated PKA and conferred cytoprotection against oxidative stress injury in human caSMCs (Supplemental Figure 8, A and B)

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Some preliminary research, primarily from animal studies with limited human data, suggests allulose may influence glucose metabolism and potentially improve insulin sensitivity, though these mechanisms remain under investigation and require further validation in robust human clinical trials

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