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18, 19, 65, 66 Given that both carnitine deficiency and PPA can be detrimental to mitochondrial metabolism, it is possible that antibiotic overuse can cause these two effects to act synergistically to cause an acquired mitochondrial disorder, especially in genetically susceptible individuals

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[PubMed] [Google Scholar] 28.Malaguarnera M, Cammalleri L, Gargante MP, Vacante M, Colonna V, Motta M