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Besides, goiter may be experimentally induced in animals exposed to goitrogenic substances, like perchlorate or thiocyanates, which block iodine uptake in the thyroid gland, causing a similar compensatory rise in secretion of TSH and hyperplasia of thyroid cells (Nourani and Sadr 2023)

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10.1002/btm2.10143 14 AramiH.KhandharA.LiggittD.KrishnanK