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To ensure evidence-based recommendations, the expert panel conducted a directed literature review followed by a rigorous three-round modified Delphi process to evaluate and finalize guidelines

The transport of choline by FLVCR1 is not significantly reduced by the addition of CCCP (Fig 2G)

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However, patients frequently ask whether they can stay on this medication indefinitely, what the long-term safety profile looks like, and whether lifetime therapy is necessary for lasting results