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Studies show that semaglutide can lead to significant weight loss in people with obesity or overweight conditions

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While a direct causal relationship is difficult to establish, patients should be advised to discontinue use and seek medical attention if they develop symptoms such as itching, yellow eyes/skin, dark urine, loss of appetite, or light-colored stools

In addition, the willingness of patients to take GLP-1 therapies is eroded by reports, such as those that appeared in the British Medical Journal earlier this year, reporting 82 deaths linked to adverse reactions in the United Kingdom

Experts advise gradually increasing the amount of weight you use and/or the number of repetitions of each movethis is called progressive overload, and its an effective way to build muscle