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For the auxin induced LAG-1 degradation time course RNA-seq experiments, lag-1(oz536oz537) and ieSi64[gld-1p :: tir1] were introduced into gld-2(q497) gld-1(q485)
The release of cathepsin D induced necroptosis through the proteolysis of caspase-8 and promotion of RIPK1 activation, implying that lysosomal dysfunction might be crucially involved in the onset of necroptosis 9
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GLP-1 receptor agonists are prescription medicines originally developed to treat type 2 diabetes, and several are now also approved for weight management