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J Pharmacol Exp Ther (2011) 339:3544 10.1124/jpet.111.182220 [DOI] [PMC free article] [PubMed] [Google Scholar] 134.Kawas LH, Yamamoto BJ, Wright JW, Harding JW

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A reduction of the N-terminal peptide bond of 25 , with the ambition to achieve a compound even more resistant to proteolytic cleavage, provided 26 ( 26 displays a Ki value in the micromolar range in sharp contrast to what could be expected considering the results obtained after reduction of Ang IV or Nle-Ang IV, cf

Glutathione levels are maintained in cells through de novo production, as well as through the recycling of its oxidized form, glutathione disulfide (GSSG)