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The good news is that severe side effects are very rare, including joint and muscle aches and pains, numbness, and swelling

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Its distinctive mechanism of action reduces the absorption of fats, potentially benefiting insulin sensitivity and reducing levels of circulating fatty acids

Heres a brief comparison: Effectiveness: While weight loss surgery typically leads to greater overall weight loss (25-35% of total body weight), the results from Zepbound (up to 22.5% in trials) are beginning to close that gap

In: Kelley WN, Harris ED, Ruddy S, Sledge CB (eds) Textbook of rheumatology