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ROS are highly reactive radical and non-radical forms of oxygen comprising superoxide anion (O 2 ), hydrogen peroxide (H 2 O 2 ), and highly reactive hydroxyl (OH) groups that are produced during oxygen metabolism during photosynthesis, oxidative phosphorylation, and peroxisomal activity 10,11

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Repurposing oncology drugs for Alzheimers: multi-omic convergence targeting cell-cycle, proteostasis, immunometabolism, and senescence