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The researchers found that there was a slight risk of developing NAION on these medications, but not much
It is important to report any new or severe symptoms to the care team
If weight loss is insufficient, usually defined as less than approximately 5% weight loss when medication-specific labeling does not specify otherwise, clinicians should reassess adherence, dose, tolerability, secondary causes of weight gain, access barriers, and whether to discontinue, switch, or intensify treatment
Over time, opioid receptors regain sensitivity, dopamine signaling stabilizes, stress systems recalibrate, and pain pathways normalize
& Pagel, H
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