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Gene expression characteristics of a cystic fibrosis epidemic strain of Pseudomonas aeruginosa during biofilm and planktonic growth

Funding This study was supported by Novo Nordisk A/S, Denmark

This was evidenced by significantly elevated levels of the pro-inflammatory lipid 9,10-DiHOME (8.0-fold), the oxidative stress marker glutathione disulfide (1.8-fold), and downstream products of the tryptophan-kynurenine inflammatory pathway, namely quinolinic acid (5.0-fold) and indole (4.0-fold)

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Over 600 carotenoids exist in nature and most of these carotenoids have antioxidant activity (e.g., -carotene)