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Three deproteinization procedures were evaluated to optimize extraction recovery, sample cleanup efficiency, and detector response

However, the co-primary endpoints of a reduction of SLE disease activity index (SLEDAI-2K) and adjusted mean SLEDAI (AMS) in patients compared with controls using a landmark analysis were not met

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Some studies suggest that DHODH activity is particularly crucial under conditions of GSH depletion, while others propose that the pathway's significance varies according to tissue type and metabolic state (80, 81)

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