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Novo Nordisk manufactures Ozempic, Wegovy, and Rybelsus using recombinant DNA technology in yeast (Saccharomyces cerevisiae) a fermentation-based biopharmaceutical process

Peptides are short chains of amino acids, the same building blocks that make up proteins

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Key therapeutic benefits include: Significant reductions in HbA1c (up to 2.02.5% in clinical trials) Substantial weight loss (up to 15% body weight reduction in type 2 diabetes and up to 22% in people without diabetes at the 15 mg dose) Cardiovascular risk factor improvements Once-weekly dosing for improved adherence Tirzepatide is not indicated for type 1 diabetes and should be used with caution or avoided in pregnancy and breastfeeding

See the chart below for a list of side effects that have been reported with these drugs