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Insilico Medicine has nominated ISM9528, an orally available, brain-penetrant non-opioid candidate targeting a previously unrecognised pain mechanism, as its 31st AI-generated preclinical compound since 2021, with efficacy exceeding morphine in some preclinical models

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This is because a standard serum test measures the total amount of B12 in your blood, not the amount that is actively available for your cells to use