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[34] [35] Naltrexone is a competitive, high-affinity antagonist at -opioid receptors and exhibits antagonistic activity at and receptors, occupying the orthosteric binding pocket without producing the conformational change required for downstream G-protein signaling

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However, both medications can cause gastrointestinal side effects, so take ibuprofen with food and use the lowest effective dose for the shortest duration

Mantener un registro visual o escritomediante un diario de inyecciones o aplicacin mvilfacilita el seguimiento sistemtico y previene la repeticin inadvertida

Pay attention to your bodys signals when you eat, and stop eating when you feel full