It also acts as an antioxidant, helping to protect cells from damage caused by free radicals and other reactive molecules
Upon activation, the NLRP3 inflammasome promotes autocatalytic cleavage of procaspase-1 into its active form, caspase-1, which subsequently processes the pro-inflammatory cytokines pro-interleukin-1 and pro-interleukin-18 into their mature forms
Glutathione injections involve the direct administration of glutathione, a naturally occurring antioxidant found in the body, through intramuscular or intravenous methods
Under pathological conditions, they may initially exert neuroprotective effects, yet prolonged activation often results in metabolic disturbances and neurotoxic gliotransmission, highlighting their dual role in CNS pathology and their potential in therapy [293]
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