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As the name indicates, an SBIR applicant must be a small businessand the government has specific criteria for eligibility, such as a company must be for-profit with 500 employees or fewer

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During apoptosis, PARP is cleaved and inactivated as part of the cell dismantling process

However, as the tumor size decreases, normal pituitary function might be expected to return and these patients therefore require frequent endocrine re-evaluation

ABHD5 ligands that release ABHD5 from PLIN1 or PLIN5 independent of PKA activation, led to the discovery of long-chain acyl-CoA (LC-CoA) as an endogenous allosteric regulator of ABHD5 that promotes the interaction with PLIN1/5 (48)