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Subsequently, Roitt et al.(6) observed that a precipitate formed when an extract of human thyroid gland was added to serum from a patient with Hashimoto's thyroiditis

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A systematic review and meta-analysis published in eClinicalMedicine found a clear metabolic rebound after discontinuation and the STEP-1 extension trial showed participants regained roughly two-thirds of the weight they had lost within a year of stopping semaglutide