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Lifestyle interventions, including exercise and nutritional approaches such as fasting or caloric restriction are often difficult to adopt, leading to low adherence and often weight cycling (loss and gain)

This FDA-approved medication works on both GLP-1 and GIP pathways

What You Can Do: Track Your Progress: Instead of focusing solely on the number on the scale, celebrate other victorieslike improved energy levels, better sleep, or smaller clothing sizes

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Clockphagy is an autophagic process that selectively degrades the core circadian clock protein aryl hydrocarbon receptor nuclear translocator-like (ARNTL/BMAL1), thereby promoting ferroptosis [212]