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Strategies that work in the backcountry: Keep medication in the center of your pack, insulated from external heat Store the pack in shade whenever possible Use natural water sources, place the sealed vial in a waterproof bag and submerge it in a cool stream to bring the temperature down At camp, hang the medication bag in shade rather than leaving it in a tent (tents become ovens in sunlight) Consider timing your trip to avoid the hottest months, or bring enough doses for a shorter trip and resume at home If your trip falls during injection day, follow the injection site guidelines and maintain proper hygiene

Persistence remains mixed: a 2024 real-world study found 32% on therapy at 1 year among non-diabetic users, and according to Prime Therapeutics, only 1 in 12 remain at 3 years

10.1016/j.ymgme.2014.10.002 44 RanjanS.NasserJ

Patients must understand that the benefits seen with FDA-approved GLP1s may not always translate to their compounded counterparts

USA 117 , 10691080 (2020)