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Studies in primary endothelial cells grown in culture, as well as in animal models illustrate that a deficiency of GPx1 alters endothelial dependent vasodilation by regulating bioavailable nitric oxide [39, 60, 61, 70, 71]

10.1016/j.yrtph.2020.104665 105 YoussefA

The commenters identified this as a potential technical error and recommended that CMS update the PC/TC indicator for CPT code 38228 from a 5 to a 0 to appropriately capture the nature of the service and to align it with other similar services such as CPT codes 38240 and 38242

Without treatment, WD is fatal and is best managed by a multidisciplinary team including neurologists, hepatologists, pharmacists and dietitians[6]

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