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These mechanisms collectively underscore the central role of GLP-1 RAs in promoting CV healthmechanisms that may likewise translate to improved erectile function, given the shared pathophysiology between CVD and ED [126]

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Transition timeline: last semaglutide dose, 1-2 week washout, tirzepatide restart at 2.5mg with 4-week titration steps

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Ferroptosis contributes to the onset and progression of AS co-depression directly or by influencing other mechanisms