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Results Endogenous MOTS-c levels increase upon exercise in humans To determine if endogenous MOTS-c responds to physical exertion, and thus may be involved in driving adaptation to enhance physical capacity, we collected skeletal muscle and plasma from sedentary healthy young male volunteers (24.5 3.7 years old and BMI 24.1 2.1) that exercised on a stationary bicycle (Fig

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Nitric oxide synthase inhibition prevents activity-induced calcineurin-NFATc1 signalling and fast- to-slow skeletal muscle fibre type conversions

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