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Glutathione and Alpha-Lipoic Acid In addition to scavenging free radicals, glutathione is also involved in recycling vitamins C and E.* Alpha-lipoic acid plays an essential role in mitochondrial dehydrogenase reactions, reacts with reactive oxygen species, and interacts with vitamin C and glutathione to recycle vitamin E.* The following table highlights two studies that looked at the effects of co-supplementation with glutathione and alpha-lipoic acid

doi: 10.1016/S0014-4827(02)00027-7 232 Vanden BergheTKalaiMDeneckerGMeeusASaelensXVandenabeeleP

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Early Developments in GLP-1 Agonists The first GLP-1 agonist, Exenatide (Byetta), was approved in 2005 and may surprise you as to where it comes from

Although large cardiovascular outcome trials have consistently shown that GLP-1 RAs, particularly semaglutide and liraglutide, reduce all-cause death in people with type 2 diabetes [9, 10], these studies did not formally stratify death outcomes by age group, limiting direct comparisons with our findings