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La scheda tecnica raccomanda inoltre di evitare luso concomitante con forti inibitori del CYP3A4 che inibiscono anche OATP1B, come ritonavir, perch il rischio di aumento dellesposizione pu diventare pi rilevante

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This is particularly important for individuals with pre-existing gastrointestinal conditions, those taking multiple medications, or anyone experiencing severe or persistent constipation that may indicate a more serious underlying issue

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Additionally, if you experience unexpected changes in blood glucose control or side effects, discuss these with your healthcare team