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Discovery of a potent, selective, and orally available MTHFD2 inhibitor (DS18561882) with in vivo antitumor activity

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HDACi directly induces apoptosis of malignant B cells in B-cell lymphoma by increasing pro-apoptotic proteins ( 2.5 Role of HDACi in enhancing natural killer cell activity Natural killer (NK) cells are crucial immune effector cells that can limit the expansion and spread of cancer cells

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K., Sapra, L